Due to the ongoing COVID-19 pandemic, our Sage Central hours have temporarily changed.
Sage Central is open M-Fri, 8am-6pm ET. For information outside of these hours, please visit SageCentralSupport.com
This site is intended for US residents aged 18 and older
Sage Central offers patient support resources and programs
This searchable database may help locate nearby REMS-certified healthcare settings that are currently accepting patients with PPD for treatment with ZULRESSO.
ZULRESSO Treating Center hours and patient/visitor guidelines may be impacted due to the ongoing COVID-19 situation. Please contact treating centers directly for the latest information.
You may have questions about the ZULRESSO infusion prior to treatment. Your doctor and healthcare team should be your primary resources for any questions regarding treatment with ZULRESSO, including selecting a Treating Center. Please enter your Zip Code, City, or State below to find ZULRESSO Treating Centers near you.
ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Because of the risk of serious harm resulting from feeling very sleepy or passing out during treatment, ZULRESSO is only available through a restricted program called the ZULRESSO REMS in which a healthcare provider will carefully monitor you at a certified healthcare facility.
Sage Central is your source for patient support resources and programs, providing information and personalized support to help navigate the PPD treatment journey.
Locations displayed are for informational purposes only.
If you are a healthcare setting listed on this Locator Tool and wish to opt out or update your information, please email support@sagecentralsupport.com
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Don’t see a center in your area?
Contact Sage Central for more information about treatment with ZULRESSO for postpartum depression (PPD).
1-844-4-SAGERX. M-F, 8am-8pm ET
Locator Tool updated as of April 13, 2021
A REMS-certified healthcare setting designated as a “ZULRESSO Treating Center” in this Locator Tool has completed the requirements to enroll and certify in the ZULRESSO REMS and has submitted evidence to Sage Therapeutics, Inc. (“Sage”) that the healthcare setting is actively accepting new patients with PPD for treatment with ZULRESSO.
Inclusion of a REMS-certified healthcare setting in the Locator Tool does not represent an endorsement, referral or recommendation from Sage and is not intended as medical advice. Inclusion of a healthcare setting in this Locator Tool is based on approval by the Authorized Representative for each healthcare setting and no fees have or will be received in exchange for participation in this Locator Tool. Moreover, the REMS-certified healthcare settings participating in this Locator Tool do not necessarily endorse the use of any Sage products.
This Locator Tool is intended to provide users with the opportunity to locate nearby ZULRESSO Treating Centers and is compiled for informational purposes only. In no event shall Sage or its employees or agents be liable for the actions of any of the healthcare settings listed herein or any damages resulting from or related to this Locator Tool. All users agree that use of this Locator Tool is at their own risk.
Sage makes no representations as to whether any of the healthcare settings included in this Locator Tool are covered by healthcare plans or insurers. Insurance verification is the responsibility of the provider and patient. Users of this Locator Tool are solely responsible for interactions with any of the listed healthcare settings, and any information sent is not governed by Sage’s Terms of Use and Privacy Policy. Users are responsible for compliance with all state and federal laws and regulations.
Contact Sage Central for more information about treatment with ZULRESSO for postpartum depression (PPD). 1-844-4-SAGERX. M-F, 8am-8pm ET. For a complete list of REMS Certified healthcare settings please visit
www.zulressorems.com.
ZULRESSO™ is a prescription medicine used to treat Postpartum Depression in adults.
IMPORTANT SAFETY INFORMATION
ZULRESSO can cause serious side effects, including: Excessive sedation and sudden loss of consciousness. ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Your
healthcare provider should check you for symptoms of excessive sleepiness every 2 hours while you are awake
What is ZULRESSO?
ZULRESSO™ is a prescription medicine used to treat Postpartum Depression in adults.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about ZULRESSO?
ZULRESSO can cause serious side effects, including:
Excessive sedation and sudden loss of consciousness.
ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Your healthcare provider should check you for symptoms of excessive sleepiness every 2 hours while you are awake
During your ZULRESSO infusion, tell your healthcare provider right away if you feel like you cannot stay awake during the time you are normally awake or if you feel like you are going to pass out. Your healthcare provider may lower your dose or stop the infusion until symptoms go away
You must have a caregiver or family member with you to help care for your child(ren) during your ZULRESSO infusion
Because of the risk of serious harm resulting from excessive sedation or sudden loss of consciousness, ZULRESSO is only available through a restricted program called the ZULRESSO REMS
Before receiving ZULRESSO, tell your healthcare provider about all your medical conditions, including if you:
drink alcohol
have kidney problems
are pregnant or think you may be pregnant. It is not known if ZULRESSO will harm your unborn baby
There is a pregnancy registry for females who are exposed to ZULRESSO during pregnancy. The purpose of the registry is to collect information about the health of females exposed to ZULRESSO and their baby. If you become pregnant during treatment with ZULRESSO, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants at 1‑844‑405‑6185 or visit
https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/antidepressants/
are breastfeeding or plan to breastfeed. ZULRESSO passes into breast milk. Talk to your healthcare provider about the risks and benefits of breastfeeding and about the best way to feed your baby while receiving ZULRESSO
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
ZULRESSO and some medicines may interact with each other and cause serious side effects.
Especially tell your healthcare provider if you take other antidepressants, opioids, or Central Nervous System (CNS) depressants (such as benzodiazepines).
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider will decide if other medicines can be taken with ZULRESSO.
How will I receive ZULRESSO?
ZULRESSO is given to you by continuous intravenous (IV) infusion into your vein. The infusion will last for a total of 60 hours (2.5 days).
What should I avoid while receiving ZULRESSO?
ZULRESSO may make you feel dizzy and sleepy. Do not drive a car or do other dangerous activities after your ZULRESSO infusion until your feeling of sleepiness has completely gone away. See “What is the most important information I should know about ZULRESSO?”
Do not drink alcohol while receiving ZULRESSO
What are the possible side effects of ZULRESSO?
ZULRESSO can cause serious side effects, including:
See
“What is the most important information I should know about ZULRESSO?”
Increased risk of suicidal thoughts or actions.
ZULRESSO and other antidepressant medicines may increase suicidal thoughts and actions in some people 24 years of age and younger. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions
How can I watch for and try to prevent suicidal thoughts and actions?
Pay close attention to any changes, especially sudden changes in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions
Tell your healthcare provider right away if you have any new or sudden changes in mood, behavior, thoughts, or feelings
Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms
Tell your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you:
Attempts to commit suicide, thoughts about suicide or dying, new or worse depression, other unusual changes in behavior or mood
The most common side effects of ZULRESSO include:
Sleepiness, dry mouth, passing out, flushing of the skin or face
These are not all the side effects of ZULRESSO.Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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