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Not actual patients.

Resources & Support

Financial assistance programs from Sage Central*

We understand cost may be a concern to many patients. Learn more about available financial assistance programs.

*Restrictions may apply. Patients with insurance provided under Medicare, Medicaid, or any other federal or state healthcare program are not eligible for financial assistance.


Eligible commercially insured patients may pay as little as $0*

Concerns about the cost of ZULRESSO® (brexanolone) should not prevent you from seeking the treatment your healthcare provider has prescribed. Sage Central offers several financial assistance programs that can help reduce out-of-pocket costs related to your treatment.

Once you’ve enrolled with Sage Central, you will automatically have access to the financial assistance programs for which you may be eligible. Your continued eligibility is subject to your satisfaction of the terms and conditions of the financial assistance programs.

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The ZULRESSO Drug Copay Assistance Program

This program is designed to help reduce eligible out-of-pocket copay costs related to the drug. If you have commercial insurance, you may be eligible for copay assistance to reduce your out-of-pocket, drug-related copay costs up to $15,000—regardless of income level* and subject to certain terms and conditions.

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The ZULRESSO Infusion Copay Assistance Program

This program is designed to help reduce eligible out-of-pocket copay costs related to the administration of ZULRESSO, which is the 2.5-day infusion. If you have commercial insurance, you may be eligible for copay assistance to reduce your out-of-pocket, infusion-related copay costs up to $2,000—regardless of income level and subject to certain terms and conditions.

(Residents of Massachusetts and Rhode Island are not eligible for infusion assistance.)

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Free Drug Program

This program provides ZULRESSO at no cost for eligible patients who meet certain income criteria and would not otherwise have access to ZULRESSO. If you are uninsured or underinsured and meet our financial eligibility criteria, you may qualify for the Free Drug Program. Subject to terms and conditions and eligibility criteria.

The Treating Center you and your healthcare provider choose for your infusion of ZULRESSO will be required to provide an attestation that it will not bill you or your insurer for any costs associated with ZULRESSO.


*ZULRESSO DRUG COPAY ASSISTANCE PROGRAM TERMS AND CONDITIONS

The ZULRESSO Drug Copay Assistance Program (the “Drug Copay Program”) helps eligible patients with private, commercial health insurance pay for a patient’s out-of-pocket costs associated with the drug up to a maximum of $15,000. Cash-paying patients and patients eligible for a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veterans Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”), are not eligible to participate in the Drug Copay Program. Sage Therapeutics, Inc., may rescind, revoke, or amend the Drug Copay Program at any time. For full patient eligibility requirements and program terms and conditions, visit SageCentralSupport.com.

ZULRESSO INFUSION COPAY ASSISTANCE PROGRAM TERMS AND CONDITIONS

The ZULRESSO Infusion Copay Assistance Program (the “Infusion Copay Program”) helps eligible patients with private, commercial health insurance pay for a patient’s out-of-pocket, infusion-related costs associated with ZULRESSO up to a maximum of $2,000. Cash-paying patients and patients eligible for a state or federally funded insurance program, including but not limited to Medicare, Medicaid. TRICARE, Veterans Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”), are not eligible to participate in the Infusion Copay Program. Residents of Massachusetts and Rhode Island are not eligible to participate in the Infusion Copay Program. Sage Therapeutics, Inc., may rescind, revoke, or amend the Infusion Copay Program at any time. For full patient eligibility requirements and program terms and conditions, visit SageCentralSupport.com.

FREE DRUG PROGRAM TERMS AND CONDITIONS

To be eligible to participate in the ZULRESSO “Free Drug Program” (the “FOP”), the patient must: (i) Be prescribed ZULRESSO for an on-label diagnosis; (ii) Have household income less than or equal to 500% of the Federal Poverty Level (FPL); (iii) Be uninsured or rendered uninsured under any of the following circumstances: (a) Patient has no healthcare insurance, (b) Patient is insured but such insurance does not cover ZULRESSO, or (c) Patient is insured with coverage for ZULRESSO, but is ineligible for the ZULRESSO Copay Assistance Programs, and cannot afford the medication (patient out-of-pocket costs are greater than $25); (iv) Reside in the United States or a U.S. territory: (v) Be treated by a healthcare professional in the United States or a U.S. territory; and (vi) Be 18 years of age or older. Patients enrolled in Medicare, Medicaid, or any other federal or state funded health plan may participate in the FOP if they receive the free product outside of their government-funded benefits. The treating healthcare provider must certify that based on their independent medical judgment, ZULRESSO is a medically appropriate treatment for the patient. The healthcare provider must agree not to bill the patient or the patient’s insurer for any costs associated with ZULRESSO and the corresponding treatment, including costs associated with the infusion of ZULRESSO (administration, needles, tubing, infusion bags, syringes, infusion pump, preparation of medication, and IV access) and hospital room and board costs. The healthcare provider must certify that they will not seek reimbursement from any third-party payer or government program for the cost of ZULRESSO or any costs associated with the infusion of ZULRESSO. The patient will be informed that they must not (i) seek reimbursement for the free drug from their health plan, and (ii) count the cost of the free drug towards their out-of-pocket spending requirements, if any, under their insurance. The free drug provided under the FOP is not conditioned on any past or future purchases. For any patient enrolled in a readily identifiable Medicare, Medicaid, or other government funded plan, Sage will send a letter to the plan informing it that: (i) the patient is receiving free product from the ZULRESSO FOP outside of the patient’s Medicare/Medicaid plan benefit, (ii) the patient and their physician have been informed that they must not seek reimbursement for the free drug from their health plan or count the cost of the free product towards the patient’s out-of-pocket spending requirements, and (iii) the plan should discontinue any pending prior authorization or coverage appeal associated with the patient.


What is ZULRESSO?

ZULRESSO® is a prescription medicine used to treat Postpartum Depression in adults.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ZULRESSO?

ZULRESSO can cause serious side effects, including:

  • Excessive sedation and sudden loss of consciousness. ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Your healthcare provider should check you for symptoms of excessive sleepiness every 2 hours while you are awake.
    • During your ZULRESSO infusion, tell your healthcare provider right away if you feel like you cannot stay awake during the time you are normally awake or if you feel like you are going to pass out. Your healthcare provider may lower your dose or stop the infusion until symptoms go away.
    • You must have a caregiver or family member with you to help care for your child(ren) during your ZULRESSO infusion.

Before receiving ZULRESSO, tell your healthcare provider about all your medical conditions, including if you:

  • Drink alcohol
  • Have kidney problems
  • Are pregnant or think you may be pregnant. It is not known if ZULRESSO will harm your unborn baby.
    • There is a pregnancy registry for females who are exposed to ZULRESSO during pregnancy. The purpose of the registry is to collect information about the health of females exposed to ZULRESSO and their baby. If you become pregnant during treatment with ZULRESSO, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants at 1‑844‑405‑6185 or visit https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/antidepressants/
  • Are breastfeeding or plan to breastfeed. ZULRESSO passes into breast milk. Talk to your healthcare provider about the risks and benefits of breastfeeding and about the best way to feed your baby while receiving ZULRESSO.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

ZULRESSO and some medicines may interact with each other and cause serious side effects.

Especially tell your healthcare provider if you take other antidepressants, opioids, or Central Nervous System (CNS) depressants (such as benzodiazepines).

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider will decide if other medicines can be taken with ZULRESSO.

How will I receive ZULRESSO?

ZULRESSO is given to you by continuous intravenous (IV) infusion into your vein. The infusion will last for a total of 60 hours (2.5 days).

What should I avoid while receiving ZULRESSO?

  • ZULRESSO may make you feel dizzy and sleepy. Do not drive a car or do other dangerous activities after your ZULRESSO infusion until your feeling of sleepiness has completely gone away. See “What is the most important information I should know about ZULRESSO?”
  • Do not drink alcohol while receiving ZULRESSO.

What are the possible side effects of ZULRESSO?

ZULRESSO can cause serious side effects, including:

  • See “What is the most important information I should know about ZULRESSO?”
  • Increased risk of suicidal thoughts or actions. ZULRESSO and other antidepressant medicines may increase suicidal thoughts and actions in some people 24 years of age and younger. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.

How can I watch for and try to prevent suicidal thoughts and actions?

  • Pay close attention to any changes, especially sudden changes in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions.
  • Tell your healthcare provider right away if you have any new or sudden changes in mood, behavior, thoughts, or feelings.
  • Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.

Tell your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you:

  • Attempts to commit suicide, thoughts about suicide or dying, new or worse depression, other unusual changes in behavior or mood.

The most common side effects of ZULRESSO include:

  • Sleepiness, dry mouth, passing out, flushing of the skin or face.

These are not all the side effects of ZULRESSO.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please also see Full Prescribing Information including Boxed Warning and Medication Guide for ZULRESSO® and discuss any questions you may have with your healthcare provider.

ZULRESSO® is a prescription medicine used to treat Postpartum Depression in adults.
IMPORTANT SAFETY INFORMATION
ZULRESSO can cause serious side effects, including: Excessive sedation and sudden loss of consciousness. ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Your healthcare provider should check you for symptoms of excessive sleepiness every 2 hours while you are awake