Resources & Support
Find a ZULRESSO Treating Center near you
For all your questions regarding your treatment with ZULRESSO® (brexanolone), including selecting a Treating Center, your healthcare provider should be your primary resource.
The information on this site is not intended to provide medical advice. Any questions should be directed to a healthcare provider.
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ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Because of the risk of serious harm resulting from feeling very sleepy or passing out during treatment, ZULRESSO is only available through a restricted program called the ZULRESSO Risk Evaluation and Mitigation Strategy (REMS) in which a healthcare provider will carefully monitor you at a certified Treating Center.
Use the Treating Center locator tool below and enter your ZIP code, city, or state to find ZULRESSO Treating Centers near you
Locations displayed are for informational purposes only. Please check with individual Treating Centers to confirm availability and local processes and guidelines.
If you are a healthcare setting listed on this locator tool and wish to update your information, please email support@sagecentralsupport.com.
A healthcare setting designated as a “ZULRESSO Treating Center” in this Locator Tool has completed the requirements to enroll and certify in the ZULRESSO REMS and has submitted evidence to Sage Therapeutics, Inc. (“Sage”) that the healthcare setting is actively accepting new patients with postpartum depression (PPD) for treatment with ZULRESSO.
This Locator Tool is intended to provide users with the opportunity to locate nearby ZULRESSO Treating Centers.
- Inclusion of a healthcare setting does not represent an endorsement, referral or recommendation from Sage and is not intended as medical advice
- Inclusion in this Locator Tool is based on approval by the Authorized Representative for each healthcare setting; no fees have or will be received
- Sage makes no representations as to whether any settings are covered by healthcare plans or insurers. Insurance verification is the responsibility of the provider and patient
Users of this Locator Tool are solely responsible for interactions with the listed healthcare settings, and information sent is not governed by Sage’s Terms of Use and Privacy Policy. Users are responsible for compliance with all state and federal laws and regulations. In no event shall Sage or its employees or agents be liable for the actions of any of the healthcare settings listed herein or any damages resulting from or related to this Locator Tool. All users agree that use of this Locator Tool is at their own risk.
Contact Sage Central for more information about treatment with ZULRESSO for PPD. 1-844-4-SAGERX. M-F, 8am-6pm ET. For a list of REMS-certified healthcare settings, please visit www.zulressorems.com.
What is ZULRESSO?
ZULRESSO® is a prescription medicine used to treat Postpartum Depression in individuals 15 years and older.
It is not known if ZULRESSO is safe and effective in individuals less than 15 years of age.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about ZULRESSO?
ZULRESSO can cause serious side effects, including:
- Excessive sedation and sudden loss of consciousness. ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Your healthcare provider should check you for symptoms of excessive sleepiness every 2 hours while you are awake.
- During your ZULRESSO infusion, tell your healthcare provider right away if you feel like you cannot stay awake during the time you are normally awake or if you feel like you are going to pass out. Your healthcare provider may lower your dose or stop the infusion until symptoms go away.
- You must have a caregiver or family member with you to help care for your child(ren) during your ZULRESSO infusion.
- Because of the risk of serious harm resulting from excessive sedation or sudden loss of consciousness, ZULRESSO is only available through a restricted program called the ZULRESSO REMS.
Before receiving ZULRESSO, tell your healthcare provider about all your medical conditions, including if you:
- Drink alcohol
- Have kidney problems
- Are pregnant or think you may be pregnant. It is not known if ZULRESSO will harm your unborn baby.
- There is a pregnancy registry for women who are exposed to ZULRESSO during pregnancy. The purpose of the registry is to collect information about the health of women exposed to ZULRESSO and their baby. If you become pregnant during treatment with ZULRESSO, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants at 1‑844‑405‑6185 or visit https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/antidepressants/
- Are breastfeeding or plan to breastfeed. ZULRESSO passes into breast milk. Talk to your healthcare provider about the risks and benefits of breastfeeding and about the best way to feed your baby while receiving ZULRESSO.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
ZULRESSO and some medicines may interact with each other and cause serious side effects.
Especially tell your healthcare provider if you take other antidepressants, opioids, or Central Nervous System (CNS) depressants (such as benzodiazepines).
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider will decide if other medicines can be taken with ZULRESSO.
How will I receive ZULRESSO?
ZULRESSO is given to you by continuous intravenous (IV) infusion into your vein. The infusion will last for a total of 60 hours (2.5 days).
What should I avoid while receiving ZULRESSO?
- ZULRESSO may make you feel dizzy and sleepy. Do not drive a car or do other dangerous activities after your ZULRESSO infusion until your feeling of sleepiness has completely gone away. See “What is the most important information I should know about ZULRESSO?”
- Do not drink alcohol while receiving ZULRESSO.
What are the possible side effects of ZULRESSO?
ZULRESSO can cause serious side effects, including:
- See “What is the most important information I should know about ZULRESSO?”
- Increased risk of suicidal thoughts or actions. ZULRESSO and other antidepressant medicines may increase suicidal thoughts and actions in some people 24 years of age and younger. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
How can I watch for and try to prevent suicidal thoughts and actions?
- Pay close attention to any changes, especially sudden changes in mood, behavior, thoughts, or feelings, or if you develop suicidal thoughts or actions.
- Tell your healthcare provider right away if you have any new or sudden changes in mood, behavior, thoughts, or feelings.
- Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.
Tell your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you:
- Attempts to commit suicide, thoughts about suicide or dying, new or worse depression, other unusual changes in behavior or mood.
The most common side effects of ZULRESSO include:
- Sleepiness, dry mouth, passing out, flushing of the skin or face.
These are not all the side effects of ZULRESSO.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Please also see Full Prescribing Information including Boxed Warning and Medication Guide for ZULRESSO® and discuss any questions you may have with your healthcare provider.
ZULRESSO® (brexanolone) is a prescription medicine used to treat Postpartum Depression in individuals 15 years and older.
IMPORTANT SAFETY INFORMATION
ZULRESSO can cause serious side effects, including: Excessive sedation and sudden loss of consciousness. ZULRESSO may cause you to feel very sleepy (excessive sedation) or pass out (loss of consciousness). Your healthcare provider should check you for symptoms of excessive sleepiness every 2 hours while you are awake